PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Can u smoke on hydroxychloroquine Plaquenil anger Recommendations released in 2016 by the American Academy of Ophthalmology for hydroxychloroquine emphasize the risk for retinopathy and suggest the dose be limited to 5 mg/kg of body weight. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require. With prolonged therapy, obtain CBCs periodically. Systemic Lupus Erythematosus. 400 mg 310 mg base PO once or twice daily; maintenance 200-400 mg 155-310 mg base PO daily. With prolonged therapy, obtain CBCs periodically. Porphyria Cutanea Tarda Off-label 100-200 mg 77.5-155 mg base PO 2-3 times/wk. Administration. Take with food or milk In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Therapeautic dose of plaquenil for lupus Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Plaquenil Dosage Guide - Plaquenil best priceG6pd chloroquineLdn and plaquenilSigns of plaquenil retinopathyPlaquenil cancer Jun 20, 2012 In an attempt to avoid these complications of therapy, trials of lower-dose cyclophosphamide have been studied for induction therapy. The Euro-Lupus Nephritis Trial compared traditional high-dose therapy, dosed monthly for 6 months followed by quarterly dosing 0.5 g/m 2 initially, then adjusted based on white blood cell count nadir, with low. Current Therapies for Lupus Nephritis - U. S. Pharmacist. Plaquenil hydroxychloroquine sulfate dosing, indications.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.