B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Plaquenil and ipl Plaquenil and veins An African American woman, aged 50 years, presents with painless “bruises” on her leg. with a blue-black to gray. Francès C, Piette J-C, et al. Hydroxychloroquine-induced pigmentation. Hydroxychloroquine-related skin discoloration. Woman in grey Hydroxychloroquine-induced hyperpigmentation. clinical features and risk factors of hydroxychloroquine-induced pigmentation. Woman With Blue-Gray Palate and Nail Beds. Melikoglu MA, Melikoglu M, Gurbuz U, et al. Hydroxychloroquine-induced hyperpigmentation a case report. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Woman in grey hydroxychloroquine-induced hyperpigmentation Skin pigmentation induced by meropenem and levofloxacin., Hydroxychloroquine-related skin discoloration Request PDF Does plaquenil help fibromyalgiaIs chloroquine still used to treat malariaDoes plaquenil help with msPlaquenil 200 mg precio colombia We herein report a case of hydroxychloroquine‐induced hyperpigmentation. A 58‐year‐old woman had a 1‐year history of asymptomatic bluish‐gray hyperpigmentation on her neck, upper trunk and upper extremities. She was diagnosed with rheumatoid arthritis 4 years prior and treated with hydroxychloroquine 200 mg/day for 4 years. Hydroxychloroquine‐induced hyperpigmentation, The Journal.. Woman With Blue-Gray Palate and Nail Beds Clinician Reviews. Gray Hair Facts What to Know to Look Your Best. Aug 14, 2013 After discontinuation of the drug, the hydroxychloroquine-associated pigmentation slowly fades. The reported time for spontaneous regression of the hyperpigmentation ranges from 2 to 6 months 6, 12; however, persistent cutaneous hyperpigmentation even 1 year after discontinuation of therapy has been observed. Pigmentation is an important factor in determining drug incorporation into hair. Results from 1211 samples of hair from healthy subjects 577 men and 634 women show that tryptophan levels are significantly higher in males 37.83±3.45 μg/g dry hair than in females 26.62±2.40 μg/g hair. Description The authors illustrate the case of a woman in her 80s with history of systemic lupus erythematosus and Sjögren syndrome. She had lost medical follow-up with her rheumatologist in the last 3 years due to progressive functional and cognitive impairment but she was still taking prednisolone 5 mg per day and hydroxychloroquine 400 mg per day for, at least, the past 11 years.