My rheumie says that although it has been proven safe, once he finds out that I'm pregnant he's going to take me off of it. Corticosteroids (such as prednisone) are generally considered safe for use during pregnancy because they do not reach the fetus in an active form.2 Cytotoxic medications such as methotrexate are stopped during pregnancy. Also one thing you have to remember is Plaquenil takes so long to enter your body to help symptoms that it will pry take just as long to leave your system so either way your body is still going to have it in it's system why go off of it throw your body off course then try to take it again, it's like starting from fresh to get your symptoms under control. Andrea I just copied this from ***** Immunosuppressant medications, which may be prescribed for severe lupus, can cause birth defects. Hydroxychloroquine side effects eye Chloroquine vs primaquine Can plaquenil cause kidney disease SLE is a multi-organ autoimmune disease that affects women of childbearing age. Early studies of women with SLE reported increased risks of preterm birth, hypertensive diseases of pregnancy and lupus flare, both during pregnancy and in the postpartum period. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. Those without a history of thrombosis were treated with low-dose prednisolone, azathioprine, or hydroxychloroquine. Pregnancy loss was reduced from 81.3% in 101 previous pregnancies to 36.8% in. I have never taken plaquenil as I have a seizure disorder as well, however, I do know that my Rheumy told me that the only safe drug to take during pregnancy is prednisone. Most certainly I wouldn't be on it if I were to have a child. Thankfully some have had successful births on prednisone but that is a strong medication just like pain medication it can harm a baby.. Hydroxychloroquine and prednisone in pregnancy Hydroxychloroquine Plaquenil, Hydroxychloroquine in lupus pregnancy - Clowse - 2006. Chloroquine hemolytic transfusion reaction Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine Side Effects, Dosage, Uses, and More. PDF Hydroxychloroquine HCQ in lupus pregnancy Double.. Hydroxychloroquine HCQ in lupus pregnancy double-blind and.. ANA+/anti-dsDNA was related to low-quality embryos, low clinical pregnancy, and early miscarriage rate. 1 Hydroxychloroquine HCQ is recommended preconceptionally and throughout pregnancy for patients with SLE, and was proved to benefit the patients with Antiphospholipid syndrome. For those women with positive ANA and ds-DNA. Not sure about the first med you listed, but I took prednisone throughout my last pregnancy for rheumatoid arthritis and had a healthy baby girl, myrheumatologist took me off my other meds, his belief was for me to take as little medication and still remain comfortable, although studies had shown no defects to the baby while on the other medications, he didnt want me to take the risk Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births. 1Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands. 2Department of Gynecology and Obstetrics, University Medical Center Utrecht, Utrecht, Netherlands.