Personally, I will be taking this when Casodex begins to fail. Bicalutamide and Chloroquine study"Taken together, our data suggest that autophagy is a protective mechanism against androgen deprivation in HRPCa cells and that chloroquine could restore hormone dependence. I also note this: "The strategy is currently being tested in clinical trials, and preliminary results are promising. Plaquenil and allergies Plaquenil mcv Prostate cancer is one of the most common malignancies. Increasing evidence suggested that endothelial cells may contribute to prostate cancer progression and metastasis. Most recently, autophagy has been proposed to plays a significant role in tumorigenesis and metastasis. Also, it is reported that downregulation of androgen receptor AR induces autophagy in prostate cancer cells. However. Unfortunately, most cases of prostate cancer are not diagnosed until they’ve reached advanced stages. The disease generally is slow growing and treatment is slow to produce results. L-arginine, also referred to simply as arginine, is a semi-essential amino acid that triggers your body to produce protein. In models where ER stress induced the apoptosis of colon cancer HCT116 cells and prostate cancer DU145 cells, autophagy may reduce cell vacuoles, alleviate the ER stress and protect cells from death 36–38. In the present study, the inhibition of autophagy in cholangiocarcinoma QBC939 cells by CQ significantly increased the expression of two. The plant contains a volatile oil with a high level of thujone (see Thuja). This set of data could lead to the development of new therapeutic strategy against HRPCa."Comments and discussion would be much appreciated... The catch, though, is that it's not always possible to give patients a high enough dose of hydroxychloroquine to have an effect on their tumor cells." "Available scientific evidence does not support claims that wormwood is effective in treating cancer, the side effects of cancer treatment, or any other conditions. Chloroquine and prostate cancer Phase I/II Study of Hydroxychloroquine With Itraconazole With., Relationship Between L-Arginine & Prostate Cancer. Plaquenil nail changesGranulomatous nodules treated with plaquenil The anti-cancer effect of the antimalarial agent chloroquine when combined with conventional chemotherapy has been well documented. To date, it was assumed that chloroquine increases the. Malaria medicine chloroquine inhibits tumor growth.. Autophagy inhibitor chloroquine induces apoptosis of.. Chloroquine & Hydroxychloroquine supporting chemo.. Herbal and Medicinal Plants Molecules Towards Treatment of Cancer A Mini Review, Lakshmi Priya. M. Bhanu Priya. K, Venkata Subbaiah Kotakadi* Josthna. P This phase II trial studies how well hydroxychloroquine works in treating patients with previously treated prostate cancer. Autophagy destroys proteins and other substances in cells and may be used by prostate cancer cells to survive. Hydroxychloroquine, which blocks autophagy, may slow the growth of and possibly kill prostate cancer cells. The Chloroquine Story in Cancer Continues. By Derek Lowe 10 February, 2016. Chloroquine’s effects on bladder cancer cell lines, it turns out, can be shut down by providing the cells with extra cholesterol, and those effects can be recapitulated by giving them statin drugs or disrupting their cholesterol synthesis pathways by RNA interference.