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    Services offering voice termination, value-added telecom solutions and a complete range of retail and wholesale voice interconnections to its customers, suppliers and partners around the world, enabling them to grow both their revenue and bottom line. Learn more Company Profile Spactron was established in 2009 as part of Monty Holding SAL. With rising demand on lower cost, higher quality and reliable telecom service, Spactron was able to become a global and fast-growing telecom solutions provider within the Monty Holding group of companies. Today it enjoys a long and proven track record in providing high-quality routes at competitive rates based on reliable technologies, as shown in the exhibits below. Counting more than 300 active bilateral interconnections through PTTs, Mobile Network Operators (MNOs), Mobile Virtual Network Operators (MVNOs), alternative operators, international carriers, calling cards' distributors, OTT’s, cable companies and service providers; Spactron always offers its customers best-quality routes at the most competitive rates anywhere in the world. In Q4 2016, Spactron has launched the Destination Specialists initiative where a dedicated destination manager is accountable for a group of 5 -10 territories, and this includes continuous testing, monitoring, trouble shooting, adding back-up suppliers and rate reductions. Spactron aims to attract all free float traffic from its partners by priding that its A2Z is fully managed. SASTAVJedna filmom obložena tableta sadrži 20 mg tadalafila. DEJSTVOTadalafil je selektivni, reverzibilni inhibitor ciklične gvanozin monofosfat (c GMP)-specifične fosfodiesteraze tipa 5 (PDE5). Fiziološka erekcija penisa nastaje tako što se usled seksualne stimuiacije iz corpus cavernusuma oslobađa azot monoksid (NO) koji aktivira enzim gvanilat ciklazu, ključni enzim u sintezi cikličnog gvanozin monofosfata (c GMP). c GMP zatim snažno relaksira glatke mišiće corpus cavernusuma, povećavajući na taj način dotok krvi i intrakavernozni pritisak, što igra najvažniju ulogu u erekciji. Specifičnom inhibicijom fosfodiesteraze 5 (PDE5) tadalafil sprečava razgradnju c GMP i povećava njegov nivo, što dovodi do produženog održavanja erekcije penisa. Tadalafil ove efekte ne ispoljava u odsustvu seksualne stimulacije. Tadalafil se dobro absorbuje nakon oralne upotrebe i maksimalnu koncentraciju u plazmi dostiže za oko 2 sata od uzimanja tablete, uz trajanje dejstva pojedinačne doze i do 36 sati.

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