It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Quinine in generic plaquenil Chloroquine gametocidal Plaquenil. Uses. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of. Side Effects. Precautions. Interactions. Methotrexate vs plaquenil side effects long term and short term I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. BACKGROUND Hydroxychloroquine is used for the treatment of rheumatoid arthritis RA and systemic lupus erythematosus SLE. Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Long term effects of plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Methotrexate vs plaquenil side effects long term and short. Hydroxychloroquine cost ukWhat blood tests are required while on plaquenilPlaquenil hydroxychloroquine side effectsCellcept and plaquenilPlaquenil and trembling Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment. If a person is going to be treated long-term with Plaquenil, they need to have a thorough dilated eye exam with best corrected visual acuity, central visual field, color vision, and dilated examination of the retina. Plaquenil Hydroxychloroquine Side Effects and Adverse Reactions. Continuation of long term treatment with hydroxychloroquine.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Retinal Damage. Neurological Disorders. Blood Disorders. Hearing Disorders. Other Side Effects. Take Plaquenil exactly as prescribed. Plaquenil comes in tablet form. It is taken once or twice a day, unless it is used for the prevention of malaria, in which case it is taken once a week beginning 1 to 2 weeks prior to traveling to an area where malaria is common.