The one where a sad little blob rolled around on screen with a rain cloud hovering over its head? That commercial first debuted back in 2001, and since then Zoloft, or Sertraline hydrochloride, has become one of the top psychiatric drugs used by American adults, according to one recent study. “Zoloft is one of the first-line antidepressant medications prescribed for both depression and anxiety, meaning it’s one of the most likely to work,” says Alison Hermann, M. D., a clinical psychiatrist at Weill Cornell Medicine and New York-Presbyterian Hospital. Zoloft is part of a class of drugs called SSRIs, or selective-serotonin reuptake inhibitors. “Their main effect has to do with changing the signaling of one of the main neurotransmitters in the brain, serotonin, which modulates mood,” explains James Murrough, M. D., the director of the Mood and Anxiety Disorders Program at the Icahn School of Medicine at Mount Sinai. Has anyone taking zoloft experienced muscle and body aches while on the medication? It seems like a lot of the anti-anxiety meds effect my muscles and cause soreness and pain. I am an avid exerciser and I have pulled and strained several muscles since starting the meds. I am on effexor now and it has a similar effect on me, it also has helped my anxiety and panic too. I also am in a constant state of overall muscle achey-ness and stiffness. So for now I ice and take advil, and deal with the pain because it's SO much better than anxiety! It seem very coincidental to me that it al started after the zoloft and has persisted since. I finally got off Zoloft after five years and now I have "feelings" again and more energy and am happier. Very stiff (rigid) muscles is a serious side effect, do contact your Doctor immediately and let him / her know what you are experinecing. As far as stiffness including joint or connective tissue pain I swear by Glucosamine, even once a day works and there are no side effects. I started taking Zoloft years ago and had what you describe My calve muscles especially and hamstrings were very tight. I just lived with it and thought it was Fibromyalgia. I got very ill with Serotonin syndrome last year and the muscle stiffness progressed to spasms and hyper reflexes, and ended with me going into "seizures' of uncontrollable jerking all over my body. For future reference: Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. I quit taking Zoloft and the muscles returned to normal. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. I had also been diagnosed with irritable bowel syndrome and that went away too. =P I am very active and it has been so hard not to be mobile and active. I agree with you, at this point my anxiety an panic disorder will be a welcome relief from all that the zoloft has done to me! Valtrex with alcohol Levitra low blood pressure Propecia brand Sertraline Sertraline belongs to a class of medications known as selective. yellowing of the eyes or skin, abdominal pain, nausea, vomiting, dark urine; low. Zoloft is an SSRI selective serotonin reuptake inhibitors antidepressant prescribed for the treatment of depression, obsessive compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. Zoloft received an overall rating of 6 out of 10 stars from 1294 reviews. I went back to taking zoloft and I just increased it by taking the whole pill now. I can't sleep, I can barely do anything without feeling a pain attack coming on and feeling. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Finding relief from spine-related back and neck pain often is not a simple or quick fix. Besides pain, other symptoms may be widespread and affect your whole life. You may feel fatigued or develop sleep disturbances. Your pain may spread from the physical to the mental and emotional. Anxiety, irritability, and depression are common if you have chronic pain, and this can certainly diminish your overall sense of well-being. That's why your doctor may recommend and prescribe an antidepressant medication as part of your multidisciplinary treatment plan. Doctors prescribe antidepressants to their back pain patients for a number of reasons—to help reduce pain and muscle tension, regain healthy sleep patterns, and of course, address the mental and emotional toll of pain. Zoloft back pain Common Side Effects of Zoloft Sertraline Hcl Drug Center - RxList, Common Side Effects of Zoloft Sertraline Hcl Drug Center. Is it legal to buy viagra from indiaDoxycycline capsules vs tabletsXanax hydrocodone Mar 9, 2014. These antidepressants — fluoxetine Prozac, sertraline Zoloft, paroxetine. skin rashes, headaches, joint and muscle pain, stomach upset. What are the real risks of antidepressants? - Harvard Health. Zoloft Reviews Everyday Health. Antidepressants Another weapon against chronic pain - Mayo.. Anti-depressants can treat chronic pain associated with diabetic neuropathy, fibromyalgia, neck pain, and low back pain. There are 3 categories of anti-depressants tricyclic anti-depressants TCAs, serotonin and norepinephrine reuptake inhibitors SNRIs, and selective serotonin reuptake inhibitors SSRIs. My back started to really bother me shortly after getting on the Zoloft. I am extremely stiff in the morning which causes extreme pain which I take vicotin and avinza for and I find if I can muster up the strength to exercise which isn't often, I stiffen up soon after which again causes more pain. Antidepressants 1st Choice for Nerve Pain. Celexa, Luvox, Zoloft, and Paxil. Pain caused by nerve tissue damage often occurs as a burning, tingling, or stabbing sensation. "The amount of.