One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. What does quinine and chloroquine treat Plaquenil and codeine Can i take ibuprofen with hydroxychloroquine Additionally, knowing the differences among toxicity symptoms in different ethnicities can help validate HCQ toxicity and find signs of it before it causes irreversible damage, Brian Toy, MD, of. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with and without antidiabetic medications. Patients treated with PLAQUENIL should be warned about the risk of hypoglycemia and the associated clinical signs and symptoms. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil toxicity signs and symptoms Drug Toxicity to the Retina and Optic Nerve Are You Missing., Plaquenil Hydroxychloroquine Sulfate Can hydroxy chloroquine affect birth controlMethotrexate plaquenil combinationMethotrexate and plaquenil for raSide affectss of plaquenilHydroxychloroquine sulphate Common Plaquenil side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Symptoms of Plaquenil toxicity are similar to other macular problems and may include Decreased fine vision or difficulty reading. Changes in Color vision. Missing Spots or shadows near the center of the vision. Jun 19, 2015 Brief Answer plaquenil toxicity Detailed Answer My dear, Thanks for sending your query to us. These drugs do have a toxicity but it is reason doctors are worried is that once toxicity occures,it continues even after stopping the drug. Otherthan retinal examination,useful information. The risk of a toxicity sharply increases after 5 years, with majority of cases of retinotoxicity occurring in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid.