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  8. kito Moderator

    Des Spence’s polemic about duloxetine [1] loses most of its power because almost every assertion he makes is wrong. Using references to support a point of view doesn’t help much when they out-of-date and superseded by new knowledge or more relevant evidence. We assume that it is not ignorance of the arguments but a deliberate attempt to provoke, despite the reasoned arguments of science. It succeeded in this because the management of chronic pain is important irrespective of what the pharma industry says. The research is dense and complex, but we know an increasing amount about the bio-psycho-social origins of pain. Research in genetics, neurobiology, and imaging have established how astonishingly complex acute and chronic pain can be; the brains of people with chronic pain are very different from those of us lucky enough not to have it. Without wanting to be comprehensive, here is a brief list of where Spence misses the point: Medicalising of chronic pain. Cymbalta for Osteoarthritis Pain - Verywell Health Duloxetine for painful diabetic neuropathy and fibromyalgia pain. Patients Deserve to Know the Truth about Cymbalta — Pain News.
     
  9. Background: UTIs are one of the most common infectious diseases encountered in out-patient departments on day to day basis. Nitrofurantoin and Ciprofloxacin are most commonly used antibiotics in the treatment of UTI. The present study was done to compare the efficacy and tolerability of nitrofurantoin and ciprofloxacin in patients of urinary tract infection. Cagnacci S, Gualco L, Debbia E, Schito GC, Marchese A. Methods: This prospective, open, randomized, parallel group, comparative study was conducted on 60 patients presenting with acute/uncomplicated or recurrent urinary tract infection in the outpatient Department of Urology, Rajindra Hospital attached to Govt. They were divided into two groups, Group I and Group II of 30 cases each. Nitrofurantoin modified release versus trimetfaoprim or co-trimoxazole in the treatment of uncomplicated urinary tract infection in general practice. European Emergence of Ciprofloxacin-Resistant Escherichia coli Clonal Groups O25: H4-ST 131 and O15: K52: H1 Causing Community-Acquired Uncomplicated Cystitis. Group I patients were put on Nitrofurantoin and Group II patients were put on Ciprofloxacin. Initially 100 patients were enrolled but only those who showed growth of uropathogens on baseline urine culture or those who completed the treatment were included in the study. Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study. The primary outcome measure was microbiological eradication on post treatment urine culture. Diagnosis and Management of Uncomplicated Urinary Tract Infections. Evaluation of efficacy and tolerability of nitrofurantoin versus. FDA Approves Once-Daily Cipro XR for the Treatment of.
     
  10. snejok New Member

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