Zoloft nursing considerations

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  1. alexcor New Member

    Zoloft nursing considerations


    Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. ZOLOFT®(sertraline hydrochloride)Tablets and Oral Concentrate Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Zoloft or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Zoloft is not approved for use in pediatric patients except for patients with obsessive compulsive disorder (OCD).

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    Nursing Drug Guide - Zoloft sertraline. gabapentin Neurontin Nursing Considerations • As needed, open gabapentin capsules and mix contents with water. Description. NRSNG Academy’s Fundamentals course is the course you’ll definitely want to have for your first semester of nursing school! We introduce the Nursing Process and how to start thinking like a nurse. Nursing implications of sertraline zoloft--assess for suicidal tendencies-- assess for s/s of serotonin syndrome--agitation, hallucinations, coma.

    25 mg, 50 mg, 100 mg tablets; 20 mg/m L liquid Potent inhibitor of serotonin (5HT) reuptake in the brain, and chemically unrelated to TCA, tetracyclic or other available antidepressants. Chronic administration of sertraline results in down regulation of norepinephrine, a reaction found with other effective antidepressants. Treats depression, obsessive-compulsive disorder, anxiety, and panic disorder. Major depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder, premenstrual dysphoric disorder, generalized anxiety, post-traumatic stress disorder. Patients taking inhibitor; antabuse; suicidal ideation, hyponatremia; mania or hypomania, pregnancy (category C); third trimester of pregnancy. Seizure disorders, major affective disorders, suicidal patients; liver dysfunction, renal impairment; abrupt discontinuation; anorexia nervosa, recent history of MI or unstable cardiac disease, dehydration; diabetes mellitus; older adults; ECT therapy, seizure disorder, seizures. Safety and effectiveness in children (shivering, nausea, diplopia, confusion, anxiety). Sertraline may increase levels and toxicity of diazepam, pimozide, tolbutamide. Use cautiously with other centrally acting CNS drugs; increase risk of ergotamine toxicity with dihydroergotamine, ergotamine. Because of the low levels of sertraline in breastmilk, amounts ingested by the infant are small and is usually not detected in the serum of the infant, although the weakly active metabolite norsertraline (desmethylsertraline) is often detectable in low levels in infant serum. Rarely, preterm infants with impaired metabolic activity might accumulate the drug and demonstrate symptoms similar to neonatal abstinence. Risk factors for poor neonatal adaptation after exposure to antidepressants in utero. Most authoritative reviewers consider sertraline a preferred antidepressants during breastfeeding.[1][2][3][4][5][6][7] Mothers taking an SSRI during pregnancy and postpartum may have more difficulty breastfeeding, although this might be a reflection of their disease state.[8] These mothers may need additional breastfeeding support. Breastfed infants exposed to an SSRI during the third trimester of pregnancy have a lower risk of poor neonatal adaptation than formula-fed infants. In a pooled analysis of serum levels from published studies and 4 unpublished cases, the authors found that 15 mothers taking an average daily dosage of 83 mg (range 25 to 200 mg) had an average breastmilk sertraline level of 45 mcg/L (range 7 to 207 mcg/L).[1] Using the average dosage and milk level data from this paper, an exclusively breastfed infant would receive an estimated 0.5% of the maternal weight-adjusted dosage of sertraline. A randomized, placebo-controlled, double-blind trial of sertraline for postpartum depression. Twenty-six women who were an average of 15.8 weeks postpartum (range 5 to 36 weeks) and receiving an average of 124 mg sertraline daily for at least 14 days for severe depression were studied while breastfeeding with extensive milk and serum sampling over a 24-hour period. All milk samples had detectable sertraline (average 129 mcg/L; range 11 to 938 mcg/L) and norsertraline (average 258 mcg/L; range 20 to 1498 mcg/L).

    Zoloft nursing considerations

    Antidepressants Nursing Pharmacology Study Guide, Sertraline Zoloft Nursing Pharmacology Considerations

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  4. Sertraline 2 mcg/L and norsertraline 12 mcg/L were undetectable in the serum of any infant.18 In a study comparing sertraline to nortriptyline for postpartum depression, 13 infants were breastfed by mothers taking sertraline dosage and extent of nursing were not stated.

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    Sertraline/Sertraline Hydrochloride/Zoloft Oral Sol 1mL, 20mg. DOSING CONSIDERATIONS. Hepatic Impairment. Dosage adjustments are recommended. Medscape - Depression, OCD, panic disorder, PTSD, PMDD-specific dosing for Zoloft sertraline, frequency-based adverse effects, comprehensive interactions. Zoloft was statistically significantly more effective than placebo as measured by the LSAS and the percentage of responders. Study SAD-2 was a 20-week, flexible dose study that compared Zoloft 50–200 mg/day, n=135, to placebo, n=69. Zoloft was titrated to the maximum tolerated dose in 50 mg increments every 3 weeks.

     
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