According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Oct appearance of plaquenil toxicity Plaquenil neck pain Plaquenil and tylenol Chloroquine phosphate Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17. Chloroquine was granted FDA Approval on 31 October. Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. As an HIV investigational drug, chloroquine is categorized as an immune modulator. 2 Immune modulators also called immunomodulators are substances that help to activate, boost, or restore normal immune function. Chloroquine is currently approved by the U. S. Food and Drug Administration FDA for the treatment of malaria and certain amoeba. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine class of drug Chloroquine - Drugs and Lactation Database LactMed - NCBI Bookshelf, Chloroquine MedlinePlus Drug Information Hydroxychloroquine inr Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury. Chloroquine - LiverTox - NCBI Bookshelf. Chloroquine Clinical Trials, Side Effects AIDSinfo. Chloroquine Indications, Side Effects, Warnings -. Chloroquine prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. Nov 25, 2019 Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.