To characterize structural changes of HCQ retinopathy with SD-OCT after drug cessation. Setting: Private practice and academic institution. Patient Population: Patients at New England Eye Center and Ophthalmic Consultants of Boston in Boston, MA diagnosed with HCQ retinopathy and followed after drug cessation. Plaquenil tongue Hydroxychloroquine and aspirin Chloroquine toxicity oct Spectral domain optical coherence tomography SD OCT images, red-free photos, and fundus autofluorescence FAF demonstrate a spectrum of findings seen with different stages of hydroxychloroquine retinopathy. Note the increased signal of choroidal vessels. Chen E, Brown D, Benz M, Fish R. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy the “flying saucer” sign Clin Ophthalmol. 2010;51–8. 16. Aug 06, 2014 Figure 2. Spectral-domain optical coherence tomography demonstrating advanced hydroxychloroquine retinopathy with parafoveal loss of the external limiting membrane, disruption of the outer ellipsoid zone, thinning of the outer nuclear layer and disruption to the underlying retinal pigment epithelial layer A. Main Outcome Measures: SD-OCT findings suggestive of HCQ retinopathy before parafoveal ellipsoid disruption. Retrospective clinical data review by the Boston Image Reading Center. Spectral-domain optical coherence tomography in hydroxychloroquine retinopathy Recommendations on Screening for Chloroquine and Hydroxychloroquine., How to Succeed in Plaquenil Screenings How long can you take plaquenil for raRetinal toxicity and plaquenil Kahn JB, Haberman ID, Reddy S. Spectral-domain optical coherence tomography as a screening technique for chloroquine and hydroxychloroquine retinal toxicity. Ophthalmic Surg Lasers Imaging. 2011;3-497. 5. Lee DH, Melles RB, Joe SG, et al. Pericentral hydroxychloroquine retinopathy in Korean patients. Ophthalmology. 2015;152-1256. 6. Retinal Physician - Hydroxychloroquine Maculopathy An.. Multimodal Imaging in Plaquenil Toxicity. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. To describe spectral-domain optical coherence tomography SD-OCT and adaptive optics AO imaging in hydroxychloroquine retinal patients with long-term hydroxychloroquine use, subtle perifoveal ophthalmoscopic pigmentary changes, and bilateral. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision Michael F. Marmor, MD,1 Ulrich Kellner, MD,2 Timothy Y. Y. Lai, MD, FRCOphth,3 Ronald B. Melles, MD,4 William F. Mieler, MD,5 for the American Academy of Ophthalmology Background The American Academy of Ophthalmology recommendations on screening for. Objective To determine whether early toxic effects from hydroxychloroquine HCQ could be detected by spectral-domain optical coherence tomography SD-OCT before symtomatic visual loss occured.