It typically happens in the evening or nighttime hours when you're sitting or lying down. Restless legs syndrome, also known as Willis-Ekbom disease, can begin at any age and generally worsens as you age. It can disrupt sleep, which interferes with daily activities. Chloroquine generic name Plaquenil medscape Chloroquine diphosphate and phosphate I had to go off Plaquenil because I did have eye problems from it but I had been on it for over 20 years. I had pains like your saying, heavy legs, aches and pains, severe fatigue. My doctor has me on meloxicam sp and savella. I was so afraid of savella because of all I have read, but decided to give it a try. I take 25 mg in the morning and. Diabetes and alcohol abuse are by far the most common causes of neuropathy in the legs. Many other conditions can cause neuropathy or a burning sensation in the feet. Heavy metal poisoning. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Medications also help many people with symptoms as abnormal, unpleasant sensations in their legs or feet. They do, however, consistently describe the desire to move their legs. Sometimes, symptoms disappear for periods of time, then come back. Simple self-care steps and lifestyle changes may help relieve symptoms. The sensations, which generally occur within the limb rather than on the skin, are described as: usually don't describe the condition as a muscle cramp or numbness. Plaquenil heavy legs Plaquenil can cause back and leg pain? What type?, Burning Sensation in Feet 19 Causes, Diagnosis, Treatment Ufo sign plaquenilAra patient information hydroxychloroquineChloroquine phosphate dosage aquariumChloroquine action and targetOmeprazole and plaquenil Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Side Effects Common, Severe, Long Term -. Restless legs syndrome - Symptoms and causes - Mayo Clinic. Be sure and rule out a possible toxic reaction to Plaquenil that can weaken your thigh muscles to the point you can't climb a flight of stairs. I had to stop taking Plaquenil in 2005 because of this reaction. Fortunately it went away after I switched to methotrexate. Also want to make sure that you have good leg circulation. I have severe muscle spasms that seem like seizures & the jerking gets real bad at times, I can t stand very long or walk for more than 10 min tops on a good day. The weakness at times leaves me bedridden and my legs feel heavy most the time which makes it difficult to walk. I too have that 'heavy' feeling in my legs where it feels almost as if you won't be able to pick up your feet and so tend to shuffle. Going up steps is very difficult as some days it is easier to move one leg than the other. I don't, however, have to be standing a lot for this to happen.