Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Bone marrow failure plaquenil Plaquenil for lupus itp Leflunomide methotrexate and hydroxychloroquine Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. My son has been diagnosed of chilblain lupus for the last 5 yrs since he was 15 yrs old. He is taking Hydroxychloroquine and Mepacrine. His white cell counts and neutrophils have dropped a couple years after his diagnosis and remained low since. Are the low counts due to his medication or his disease? Can anybody advise? Thanks Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can hydroxychloroquine affect neutrophils What can Hydroxychloroquine Plaquenil do to my eyes?, Low white cell counts and neutrophils My son has. - LUPUS UK What class of drug is hydroxychloroquine sulfatePlaquenil rheumatoid arthritis renalVertigo from plaquenil Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects Common, Severe, Long Term -. Do either hydroxychol/Plaquenil put you at risk for greater.. Will you have Lymphocyte count decreased with Plaquenil.. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. What are some other side effects of Hydroxychloroquine? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARDregulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms.