No clinical trials of medications for ch ILD have been conducted to date. Corticosteroids have been the mainstay of therapy in most children and adults with interstitial lung disease (ILD), despite little conclusive evidence of their efficacy. Malaria hydroxychloroquine resistance Plaquenil low heart rate Hydroxychloroquine and Surfactant Protein C Deficiency This article has no abstract; the first 100 words appear below. To the Editor We wish to report initial success in treating a boy with. Childhood interstitial lung disease due to surfactant protein C deficiency frequent use and costs of hospital services for a single case in Australia Neil J Hime 1, 2 Dominic Fitzgerald 2, 3 SFTPC surfactant protein C mutations resulting in SP-C deficiency causing ongoing respiratory failure in the neonatal period represent a rare entity. These agents elicit anti-inflammatory properties and cause profound and varied metabolic effects. The medications commonly used for pharmacotherapy in ch ILD and common adverse effects are reviewed below. Hydroxychloroquine surfactant protein c deficiency Hydroxychloroquine and Surfactant Protein C Deficiency., Childhood interstitial lung disease due to surfactant. Cheap aralen prescribingBuy plaquenil online ukEffect of plaquenil on free light chainsChloroquine for malaria in pregnancyPlaquenil and feeling sick In a recently published report, three infants with SP-C deficiency due to an I73T mutation and unusually early respiratory symptoms carried an additional mutation in the ATP binding cassette protein A3 gene ABCA3, a phospholipid carrier essential for lamellar body formation and surfactant intracellular assembly. Surfactant Protein C-associated interstitial lung disease.. Successful treatment of neonatal respiratory failure.. Successful weaning from mechanical ventilation in a.. Lung transplantation was successful in children with SFTPC gene mutation as noted in one case report. 4 Few cases of surfactant protein C deficiency treated with hydroxychloroquine have been. Chest Radiographs and a CT Scan in a Boy with Surfactant Protein C Deficiency Treated with Hydroxychloroquine. Panel A shows a chest radiograph and Panel B a CT scan obtained at the initiation of. While most surfactant deficiencies are secondary to prematurity or lung injury and infection, hereditary surfactant protein B deficiency, caused by mutations in the surfactant ommbid. With surfactant deficiency, a greater pressure is needed to open the alveoli.