Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and chronic fatigue syndrome Plaquenil malaria dose According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Feb 19, 2020 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. PRECAUTIONS Before taking hydroxychloroquine, tell your doctor or pharmacist if you are allergic to it; or to other aminoquinolines e.g. chloroquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can hydroxychloroquine cause mental problems PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses How does plaquenil fight malaria With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage. Protecting your eyesight when taking Plaquenil Lupus.. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Rx Side Effects New Plaquenil Guidelines and More - American.. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. The other thing is your hydroxychoroquine. I am hypersensitive to meds, they often cause all sort of reactions in me, one of which is severe fatigue. certain brands are worse then others. I can only take hydroxyl made by "Sentiva" the generic brands make me quite ill, with one of the symptoms being extreme fatigue. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.