Sertraline is categorized as an SSRI drug, and is considered a potent serotonin reuptake inhibitor. However, it also is sometimes called an SDRI drug, referring to the drug’s secondary (weaker) dopamine reuptake inhibiting characteristic. It has been suggested, though not conclusively proven, that increasing dopaminergic as well as serotonergic activity may be relevant to medication-based treatment of depression. (1) Like all SSRI drugs, Zoloft can produce certain side effects and adverse effects that may be experienced when withdrawing from the drug. Below we will present information on these topics and others that appear to be some of the most common questions and searches done on the drug. As previously mentioned, Zoloft (sertraline) is a drug used to treat adult MDD (major depressive disorder). The Black Box warning on the drug’s packaging contains warnings which indicat the drug should not be prescribed to anyone under the age of 25, due to known increase of suicidality. In a placebo-controlled, double-blind, randomized study of the comparative abuse liability of ZOLOFT, alprazolam, and d-amphetamine in humans, ZOLOFT did not produce the positive subjective effects indicative of abuse potential, such as euphoria or drug liking, that were observed with the other two drugs. Contact Pfizer Safety to report an adverse event, side effect or concern about the quality of a Pfizer product: (800) 438-1985 You may also contact the U. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns at 1-800-FDA-1088 or gov/Med Watch If you are looking for information about Pfizer studies currently recruiting new patients in your area, you can begin your search on our website. For questions about a Pfizer Clinical Trial, call (800) 718-1021 or email Pfizer Rx Pathways® connects eligible patients, regardless of their insurance status, to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings. For more information, please call (844) 989-7284 or visit Eligible patients can register for valuable savings offers for nearly 40 brand name medications. Levitra with dapoxetine Generic zithromax azithromycin Can doxycycline be crushed Apr 15, 2013. Learn about Zoloft addiction symptoms, signs, side effects, statistics and causes of Zoloft abuse and withdrawal. Addiction Hope offers free. Sertraline is not addictive, but it can cause 'withdrawal' or discontinuation effects if stopped like prescription drugs, possible to abuse antidepressants you get high off the drugs? Jul 29, 2016. If you take Zoloft, you may wonder if you can drink. We'll explain if it's safe to. One drug commonly used to treat depression is Zoloft. Zoloft is a prescription. Learn more about alcohol abuse with Paxil and READ MORE. Sertraline is an effective antidepressant acting as a selective serotonin reuptake inhibitor. The subjective and behavioral effects of sertraline were studied and compared with the effects of alprazolam and dextroamphetamine in a within-subject, randomized, double-blind study in 20 volunteers aged 18 to 46 years. These subjects were experienced but nondependent users of central nervous system depressants who had the ability to reliably distinguish secobarbital, 150 mg, from placebo and to report positive subjective effects of secobarbital in an experimental setting. The following drug conditions were tested: sertraline, 100 and 200 mg; alprazolam, 1 mg; dextroamphetamine, 10 mg; and placebo. Drug effects were assessed with an objective test of psychomotor performance, subject-rated questionnaires, and observer-rated scales. Both alprazolam and dextroamphetamine were distinguishable from placebo on most measures, but sertraline produced effects discernable from placebo on only a few measures. At 1 hour postdrug administration, dextroamphetamine and alprazolam produced positive effects on several measures of elation, euphoria, and drug liking greater than placebo and both doses of sertraline. In a recent NIDA-funded study, the antidepressant sertraline (Zoloft) made quitting methamphetamine harder. The researchers hypothesized that the sertraline might alleviate these symptoms and promote abstinence because: The team recruited 229 men and women who were addicted to methamphetamine. Prescribed to relieve depression during the methamphetamine withdrawal process, sertraline produced a number of unpleasant side effects and may have interfered with behavioral interventions as well. All were between the ages of 18 and 65, and all were seeking treatment. The researchers performed baseline testing and encouraged the participants to stop taking methamphetamine with the help of twice-weekly recovery skills groups. Walter Ling, and their colleagues at the University of California, Los Angeles (UCLA) noted that methamphetamine abusers in withdrawal frequently complained of fatigue, lack of pleasure, sad mood, and persistent daytime sleepiness. At the end of 2 weeks, they randomly assigned the participants to one of four groups: sertraline with contingency management (CM), sertraline alone, placebo with CM, and placebo alone. All participants provided urine samples on Mondays, Wednesdays, and Fridays and attended a 90-minute psychological support group three times a week based on the Matrix Model relapse prevention program. This standardized, manual-driven model is evidence-based and incorporates social learning, behavioral and cognitive therapies, and psychological and HIV-risk education. In addition, the sertraline group reported significantly more sexual, gastrointestinal (including nausea), and anticholinergic side effects. Sertraline abuse Antidepressant Addiction and Abuse - Addiction Center, Is The Drug Sertraline Addictive? - YouTube Prednisone inhaler ZOLOFT 50 mg tablets white film-coated tablets marked with the Pfizer logo on. randomised study of the comparative abuse liability of sertraline, alprazolam. Zoloft - Medsafe. Can I Mix Zoloft and Alcohol? - Healthline. Zoloft Sertraline Side Effects, Withdrawal and FAQs. Sertraline, sold under the trade name Zoloft among others, is an antidepressant of the selective. In accordance, while sertraline has very low abuse potential and may even be aversive at clinical dosages, a case report of sertraline abuse. Sertraline is the generic name for the blockbuster antidepressant medications Lustral and Zoloft. The medication was approved by the Food and Drug Administration in the United States to treat several. Zoloft sertraline is an antidepressant from the class of selective serotonin reuptake inhibitors SSRIs. Learn how it is used in drug rehabs.