This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. 1h chloroquine binding biochemistry and biophysics Can plaquenil cause hypoglycemia Plaquenil et douleurs articulaires One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Side effects of chloroquine on eye Compare Plaquenil vs Chloroquine -, Hydroxychloroquine-Induced Retinal Toxicity - American. Chloroquine resistant plasmodium falciparum treatmentIc hydroxychloroquineGlioblastoma chloroquine What are the side effects The most feared side effect is that of loosing vision. On the doses of chloroquine which are used today the risk of eye damage is very small. When antimalarials were first used for arthritis they were used in much higher doses than at present. Plasmoquine - what side effects DailyStrength. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Chloroquine Indications, Side Effects, Warnings -. Tell your doctor right away if you experience any of the following severe side effects Unusual behavior or mood changes. Severe diarrhea. Vision problems or blurred vision. Trouble reading words or seeing parts of objects. Sensitivity to sunlight. Hearing loss. Ringing in the ears. Change. Along with its needed effects, chloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine Incidence not known. Anxiety; attempts at killing oneself Ask questions about non-ocular side effects as well. Only two third of patients comply with therapy, and most non-adherence to therapy are in patients under 80 kilograms in weight, likely because of an increased incidence of side effects. Common, nonocular, side effects of chloroquine and hydroxychloroquine include pruritus, headaches.