Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine inhibits autophagy in mice Chloroquine injection medication Plaquenil oral lichen planus What is the correct way to discontinue use of plaquenil. but you better get back on before the summer or you could experience a flare-up. I have been on. On plaquenil always made me feel very bad. hate it. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. it was so bad I just came off it for several months. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. Plaquenil hydroxychloroquine "I've been on and off Plaquenil for 13 years for Undifferentiated connective tissue disease UCTD. I have NEVER had a flare while on plaq. The only times I've had flares was when I stupidly stopped taking plaq. That is a mistake I will never make again, after a life threatening flare in 2015. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can u still have a flare while on plaquenil Plaquenil -, When starting hydroxychloroquine do symptoms feel. - LUPUS UK Using hydroxychloroquine and leflunomide together I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I have not been formally diagnosed yet. It took 6 weeks to see the results. I went into a bad flare. Went back to rheum and he decided to put me on Methotrexate. I have only taken it once, so I am not sure what the results will be. Stopping Plaquenil - General Discussion - Life With Lupus. User Reviews for Hydroxychloroquine to treat. -. Can you still flair when taking Plaquenil? - HealthBoards. And, you should have regular eye screenings the entire time you take the medication. While eye damage only occurs in about 1 in 5,000 people that take the drug for at least 5 years, it is important to monitor. It is crucial that you do NOT smoke while taking Plaquenil, or other antimalarial medications. Be sure to notify your ophthalmologist that you are taking this medicine so you can have the correct visual screening tests. Every person starting Plaquenil should have a baseline ophthalmologic exam within the first year, see the section below on How to use Plaquenil for things to ask for during your visit and regular screenings thereafter. Lupus-- also called systemic lupus erythematosus, or SLE -- might not have a cure, but it's a highly treatable condition. Lupus medications can help lower long-term risks and keep symptoms under.