Hydroxychloroquine as third-line agent in type 2 diabetes

Discussion in 'Chloroquine' started by sad37, 27-Feb-2020.

  1. Laura User

    Hydroxychloroquine as third-line agent in type 2 diabetes


    Detailed information on how Wiley uses cookies can be found in our Privacy Policy. No matter where you are with type 2 diabetes, there are some things you should know. Type 2 means that your body doesn't use insulin properly.

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    Patients with type 2 diabetes mellitus often begin treatment by taking oral agents, usually metformin or a sulfonylurea, and then progress to the combination of these two agents. Most patients often require three or more agents or a change to an insulin regimen. The aim of the study was to evaluate the clinical safety and efficacy of hydroxychloroquine in subjects with were poorly controlled type 2 diabetes mellitus T2DM, despite treatment with insulin glargine and a combination of gliclazide and metformin. 105 patients with type 2 DM, mean age 56.84 years and mean body mass index BMI 26.30 kg/msup2/sup, were enrolled in this multicentre open. The median duration of hydroxychloroquine exposure was 14.0 months. Of the 48 cases developing diabetes during observation, 3 were exposed to hydroxychloroquine at time of development and 45 were nonexposed, yielding incidence rates of 6.2 and 22. per year P = 0.03, respectively.

    Regardless, you have everything you need to fight it. And while some people can control their blood sugar levels with healthy eating and exercise, others may need medication or insulin to manage it.

    Hydroxychloroquine as third-line agent in type 2 diabetes

    Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Efficacy of Hydroxychloroquine as an Add on Drug with Basal Insulin.

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  4. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.

    • Hydroxychloroquine - Wikipedia.
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    Efficacy and safety of hydroxychloroquine in the treatment of type 2 diabetes mellitus a double blind, randomized comparison with pioglitazone. Pareek A1, Chandurkar N, Thomas N, Viswanathan V, Deshpande A, Gupta OP, Shah A, Kakrani A, Bhandari S, Thulasidharan NK, Saboo B, Devaramani S, Vijaykumar NB, Sharma S, Agrawal N, Mahesh M, Kothari K. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. IBackground./i Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia. It affects millions of people globally. In spite of many antidiabetic drugs that are available, an adequate level of control remains challenging. Hydroxychloroquine is an immunomodulatory drug that has been used for the treatment of malaria and autoimmune diseases. There is an.

     
  5. Smorodin Guest

    This is not a list of all drugs or health problems that interact with chloroquine. Chloroquine Protects Against Zika In Vitro The Scientist. Chloroquine - an overview ScienceDirect Topics Chloroquine - Prescription Drug Information.
     
  6. Z-art Well-Known Member

    Plaquenil hydroxychloroquine sulfate dose, indications, adverse. Hydroxychloroquine is a CYP2D6 inhibitor, while cobicistat is a substrate of CYP2D6. Dasatinib Major Avoid coadministration of hydroxychloroquine and dasatinib. Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval.

    Plaquenil - FDA prescribing information, side effects and uses