Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Plaquenil corneal deposits Saltwater fish chloroquine compatible with acrifulvine What areas are chloroquine resustant Plaquenil and heart Plaquenil is better than Sulfazalizine but the Arava is still more effective than the Plaq. Can't imagine Plaquenil by itself being very effective for moderate to severe. only good for mild cases. Keep in mind that Arava can really take a full three months to acheive full effectiveness. keep taking Plaq until then. With Plaquenil, the possibility of permanent vision damage scares me. I also want to be sure that I'm taking a drug that will slow/stop the progression of the disease. I've read elsewhere that Plaquenil is not as strong/effective in the treatment of early RA. With Methotrexate, the reports of nausea and possible liver damage are concerning. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Is plaquenil safer than methotrexate Methotrexate for RA Side Effects, Effectiveness, Plaquenil vs Methotrexate rheumatoid - reddit Side affectss of plaquenilPlaquenil cause itching January 2, 2013. One Chick is looking for your advice on medication My Rheumatologist recommended Methotrexate for my RA which I haven’t started taking yet because I was waiting until after the holidays in case I have side effectshowever she mentioned Plaquenil but she felt the Methotrexate is better for my RA. Member Discussions and Questions Advice Needed for.. Compare Plaquenil vs Methotrexate -. Methotrexate or Plaquenil - Scleroderma - Inspire. I havent had any side effects but I guess it is early days yet. The RA is better but I am putting that down to the steroid injection rather than the plaquenil as I have been told the Plaquenil can take a few weeks to work. Its interesting to read everyone elses views on the different drug treatments lixxie7 Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. I told my doctor I wanted to research a bit before I gave an answer. Do you think I should try the Plaquenil first before starting MTX or is it fine to jump to MTX? From what I read so far, seems like methotrexate is a bigger drug with more side effects so plaquenil would be the better choice. Any information would be helpful.