It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and sarafem interactions Chloroquine cytotoxic Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. One thing to keep in mind, make sure they test thoroughly for Crohn's disease. They usually can rule that out with the colonoscopy, but sometimes it can only be in the small intestine which they can't always see. I have been on Plaquenil and can tell you my diarrhea started within days of starting the med. My doctor warned me that diarrhea. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil for crohn's Hydroxychloroquine Uses, Dosage & Side Effects -, Plaquenil, diarrhea and weight loss? - Sjogren's World Pharmacological treatment with chloroquine inhibits autophagy in vivoHydroxychloroquine pigmentation histology There is growing consensus that Crohn's disease CD results from an altered relationship between the immune system and intestinal bacteria.1 Changes in the fecal microbiota, particularly decreased diversity,2 are also found in animal models of gut inflammation,3 but the mucosa-associated microbiota shows more specific changes, even in inactive disease. Killing of Escherichia coli by Crohn's Disease Monocyte-derived.. Hydroxychloroquine Side-effects, uses, time to work. Plaquenil oral Reviews and User Ratings Effectiveness, Ease of Use.. There is growing evidence that Crohn's disease may be caused by replication of bacteria, perhaps particularly E. coli, within macrophages a specialized sort of white blood cell. Laboratory studies show that a combination of antibiotics that can penetrate macrophages such as ciprofloxacin and doxycycline together with the anti-malarial drug hydroxychloroquine which makes the contents of. I had severe nausea and diarrhea when started on Plaquenil 2 X 200mg tabs once daily almost 3yrs ago. As I also have Crohn's Disease and an Ileostomy this was putting me at serious risk. I was told to stop the Plaquenil until my GI symptoms disappeared. Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D. for their abilities to kill E. coli and generate neutrophil chemoattractants and also assessed the effects of hydroxychloroquine HCQ and vitamin D on killing of phagocytosed E.