Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Safe to take plaquenil with antacids Joint task force-bravo chloroquine 1989 CN is a 75yo WF who is taking Coumadin. She is started on Isoniazid at the local health department. When she started therapy, she was told that she needs to have her INR checked regularly. She calls the TB clinic to report that her check up showed her INR had increased out of range after taking the medication for 3 months. What should happen now? Medicines that may cause Plaquenil interactions include digoxin, cyclosporine, and mefloquine. This eMedTV resource contains a more detailed list of drugs that may interact with Plaquenil and describes the potential effects of these interactions. Warfarin sodium and Plaquenil drug interactions - a real-world study. Summary Drug interactions are reported among people who take Warfarin sodium and Plaquenil together. This study is created by eHealthMe based on reports of 204 people who take Warfarin sodium and Plaquenil from Food and Drug Administration FDA, and is updated regularly. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and coumadin interaction Rx Side Effects New Plaquenil Guidelines and More - American Academy., Plaquenil Interactions - Antibiotics Home Page Chloroquine mechanism of action autophagyHydroxychloroquine and leflunomide togetherAcid reflux and plaquenilAmaurosis fugax from plaquenilPlaquenil tablets hydroxychloroquine sulphate View interaction reports for hydroxychloroquine and the medicines listed below. Advil ibuprofen Aleve naproxen amitriptyline. amoxicillin. aspirin. Aspirin Low Strength aspirin Benadryl diphenhydramine . Warfarin sodium and Plaquenil drug interactions - eHealthMe. Drug Interactions With Hydroxychloroquine. Our results regarding blood hydroxychloroquine and desethylchloroquine concentrations in 223 treated patients did not show any significant relationship between cigarette smoking and hydroxychloroquine or desethylchloroquine concentrations. This is a strong argument against a direct effect of smoking on hydroxychloroquine metabolism. Plenty of people take both Plaquenil and Coumadin without problems but there definitely are therapeutic problems from time to time. Raglet's advice is spot on. I don;t know of any reason not to stuff yourself with Vitamin K rich foodstuffs, just mention to your doctors that you are doing this- I have no idea how long it takes to reduce the anti. Acetaminophen, an analgesic that is commonly used worldwide, is often preferred to NSAIDs due to its more appealing adverse effect profile. Up to 18% of patients taking warfarin also take acetaminophen, but clinicians may not recognize the potential interaction between the two medications.