Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. When do you use hydroxychloroquine in rheumatoid arthritis Chloroquine lysosomal inhibitor transfection Plaquenil and tingling hands Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage. HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus is also used to treat malaria. The lowest GoodRx price for the most common version of generic Plaquenil is around $20.41, 88% off the average retail price of $177.73. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Common side effects of plaquenil Plaquenil Side Effects on Your Eyes and Vision, Plaquenil Side Effects - GoodRx Plaquenil visual side effectsChloroquine selleckchemChloroquine resistant malaria definition Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine Uses, Dosage & Side Effects -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. These side effects are nothing to be concerned about, but if they start to worsen, then you may seek medical help immediately. Remember that you have been prescribed this medication because your doctor believes that the benefits of Plaquenil are more significant than the side effects. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. Although all risk cannot be excluded it remains a treatment for rheumatic disease during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication.