From that excerpt it appears as that Cymbalta may cause a slight liver enzyme elevation. That does not mean that Cymbalta causes fatty liver. Fatty liver is a disorder in which fatty deposits accumulate in the liver. This disorder is more frequently seen in overweight patients but that is not always the case - people who are not overweight can also develop this disorder. There is presently no medical treatment for fatty liver. Your liver filters everything you eat, drink and do. I just wrote a book called Living in a Place called Beautiful, by Brooke Jennings. Jaundice, or yellowing of the skin and eyes, may be present. If your taking drugs you can ruin your liver and that my dear can cause a fatty liver, hepatitis a, b, c and cirrhosis. They can lead to an early death and other health issues. Cymbalta may interact with alcohol and injure the liver and should not be used by people who use alcohol regularly. It is not however any direct effects of the drug on the liver. Read more This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. If you gained weight while on Cymbalta (duloxetine) then indirectly it could cause fatty liver. Rather, it would be more of a direct effect of the drug on your appetite. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of Fatty liver is a benign condition usually related to diet, however if it worsens it can become a condition called steatohepatitis. Gallstones are typically harmless unless a stone gets caught in a duct. It can be caused by a variety of things but each can cause cellular damage to the liver, then fibrosis, then even cirrhosis and liver failure. Read more See 2 more doctor answers This is a disease where fat is abnormally deposited in the liver. Some people with a long family history of gallbladder problems get the gallbladder removed, but most people have gallstones all their life without problems ... Obesity, pre diabetes and type 2 diabetes are causing non alcoholic fatty liver at an alarming rate, even in young kids. It can lead to inflammation and ultimately cirrhosis. Read more Several things can contribute to fatty infiltration of the liver including 1) excess weight over a long period of time, 2) pregnancy, 3) diet 4) medical conditions like diabetes, and 5) medications including chemotherapy. It is the most common liver disease in the US and is related to obesity, diabetes, elevated triglycerides and genetics. Read more See 1 more doctor answer Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Depending on the contributing factors, some of the problem may be treated effectively with weight loss, tight glucose control, and/or dietary modification. Read more See 3 more doctor answers Fatty liver, especially from etoh & chronic hepatitis associated with cirrhosis (scarring throughout the liver & progressive liver failure, not reversible & leads portal hypertension, recurrent stomach./intestinal bleeding, feeling terrible & early death). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Best zoloft dose for anxiety Xenical cap 120mg A small number of children, teenagers, and young adults up to 24 years of age who took antidepressants ''mood elevators'' such as duloxetine during clinical studies became suicidal thinking about harming or killing oneself or planning or trying to do so. Duloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. Some people may have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. From that excerpt it appears as that Cymbalta may cause a slight liver enzyme elevation. That does not mean that Cymbalta causes fatty liver. Fatty liver is a disorder in which fatty deposits accumulate in the liver. Do not take duloxetine if you have taken an monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan®], linezolid [Zyvox®], methylene blue injection, phenelzine [Nardil®], selegiline [Eldepryl®], or tranylcypromine [Parnate®]) in the past 2 weeks. Do not start taking an MAO inhibitor within 5 days of stopping duloxetine. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, or severe convulsions. Duloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. Some people may have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. If you or your caregiver notice any of these unwanted effects, tell your doctor right away. If you’re prescribed to it, what should you know about the potential interaction between alcohol and Cymbalta? The following is some important information about Cymbalta in general, as well as alcohol and Cymbalta., a prescription drug that’s part of the class of drugs known as serotonin-norepinephrine reuptake inhibitors or SSNRIs. When you take SSNRIs, it changes the balance of chemical neurotransmitters in your brain including norepinephrine and serotonin. Cymbalta can be prescribed for generalized anxiety disorder, depression, and nerve damage pain related to depression. It can also be used to treat the symptoms of fibromyalgia, which is a chronic pain condition. There are some possible side effects seen with Cymbalta, even when you’re not looking at the interaction between alcohol and Cymbalta. Some of the side effects can include weight gain or weight fluctuations as well as fatigue, dry mouth, nausea, constipation or diarrhea. Duloxetine liver Alcohol and Cymbalta Craving, Blackout, and Side Effects, Duloxetine Oral Route Precautions - Mayo Clinic Lasix copd Duloxetine, sold under the brand name Cymbalta among others, is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. It is taken by mouth. Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Severe side effects include an increased risk of suicide. Duloxetine - Wikipedia. Cymbalta and fatty liver - MedHelp. Cymbalta duloxetine dose, indications, adverse effects.. Patient Education DULOXETINE - ORAL IMPORTANT NOTE The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. The treatment is weight loss. If you gained weight while on Cymbalta duloxetine then indirectly it could cause fatty liver. It is not however any direct effects of the drug on the liver. Rather, it would be more of a direct effect of the drug on your appetite. Best wishes. Duloxetine hydrochloride is a white to slightly brownish white solid, which is slightly soluble in water. Each capsule contains enteric-coated pellets of 22.4, 33.7, or 67.3 mg of duloxetine hydrochloride equivalent to 20, 30, or 60 mg of duloxetine, respectively. These enteric-coated pellets are designed to prevent degradation of the drug in the acidic environment of the stomach.