Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and osteoarthritis Hydroxychloroquine method of action Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Hydroxychloroquine Plaquenil hydroxychloroquine. 4 alternatives. Arava leflunomide. methotrexate methotrexate. Sulfasalazine sulfasalazine. chloroquine chloroquine. Is there a drug that I can take to replace plaquenil? Asked by tanner01. there are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. i researched these drugs before i. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil substitute Hydroxychloroquine - Plaquenil Alternative - LUPUS UK, Plaquenil hydroxychloroquine Alternatives & Similar. Plaquenil ibuprofen interactionPlaquenil 200mg prospectTaking plaquenil while having infectionsPlaquenil mycoplasmaHydroxychloroquine surfactant deficiency Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. I hope this was helpful enough. Alternatives to plaquenil Anti-Inflammatories.. Is there a drug that I can take to replace plaquenil?. Compare Plaquenil vs Chloroquine -. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Nothing safer Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not. Certified integrative health coach Luanna Barker of New York says that RA and lupus patients who have to stop taking Plaquenil can focus on alternative methods of treatment in the interim, until.