How to order a prednisone taper

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  1. quzzy Well-Known Member

    How to order a prednisone taper


    Although PMR is the prototype of glucorticoid (GC)-responsive disease, the use of GC is mainly based on empirical knowledge. It is probably because of the dramatic response of PMR to GC that randomized controlled trials of treatment are lacking. We know that GCs are an effective treatment, that they nearly always induce short and medium time disease remission, and that they often cause side effects. However, the list of incomplete or absent information is long. In particular we do not know: Which is the best initial GC dose: If we can predict it in the individual patient (by gender, BMI, disease characteristics, etc.). The optimal glucocorticoid starting dosage is not defined yet, and varies widely across different studies, being comprised between 7 mg and 25 mg prednisone. The only controlled study suggests that initial prednisone doses ≤10 mg are associated with high incidence of recurrences at 2 months, whereas doses ≥20 mg are associated with considerable side effects. Reduce the dose by 5mg every 3 days until complete. With steroid drugs, it is important to slowly reduce the dosage over a period of time, which is often called 'tapering'. 99 tablets Reply (by Keith)Prednisone is a corticosteroid.

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    How to order a prednisone taper

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