Chloroquine antibiotic

Discussion in 'Canadian Pharmacy Drugs Online' started by Malvinka, 10-Mar-2020.

  1. roopayvof Moderator

    Chloroquine antibiotic


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Singh said eradicating drug-tolerant bacteria using Chloroquine was likely to inhibit the evolution of drug-resistant MDR/XDR strains of Mtb. “This study provides a solid foundation to initiate human clinical trials to shorten antibiotic treatment of tuberculosis using Chloroquine in combinations with anti-TB drugs. Chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine antibiotic

    Hydroxychloroquine Uses, Dosage & Side Effects -, Medicines for the Prevention of Malaria While Traveling.

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  4. Chloroquine-resistant P. falciparum first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted.

    • CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and Deaths Be..
    • Chloroquine Oral Route Proper Use - Mayo Clinic.
    • Chloroquine - FDA prescribing information, side effects and uses.

    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted. P. falciparum has also developed resistance to nearly all of the other currently available antimalarial drugs, such as sulfadoxine/pyrimethamine, mefloquine, halofantrine, and quinine. The antibiotic azithromycin - which is known to be effective against secondary infections from bacterial lung disease - led to even better outcomes. Professor Raoult said the results showed there was "a spectacular reduction in the number of positive cases" with the combination therapy.

     
  5. Kroha123 Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Clinical Pharmacokinetics and Metabolism of Chloroquine. Dose Optimization of Chloroquine by Pharmacokinetic Modeling. Hydroxychloroquine - Wikipedia
     
  6. Skom Moderator

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine - Drug Central Is Hydroxychloroquine As Effective As Phlebotomy for. Porphyria cutanea tarda Recent update - ScienceDirect
     
  7. Kopona Guest

    Hydroxychloroquine Plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Hydroxychloroquine - Wikipedia
     
  8. MishaA New Member

    PLAQUENIL HYDROXYCHLOROQUINE SULFATE, USP WARNING PHYSICIANS. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients Dibasic Calcium Phosphate, Hydroxypropyl Methylcellulose, Magnesium Stearate,

    DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet