Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil prescribed by rheumatologist cut in half Hydroxychloroquine and t cells Dr. Freedman, whose expertise is related to diseases involving the mouth, including autoimmune processes, presented a lecture on the effects of lupus and oral health. He began by informing the audience that there are three major categories of lesions that occur in the oral cavity of people with lupus Sadly the Pred connection doesn't work for me. Taste problems started before I was ever put on Pred and have now been off it since August. Wish that was the answer. I guess you could say I am learning to live with it since I don't notice it as much anymore. I just avoid the foods that really taste bad to me and the others I have learned to. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Effects of hydroxychloroquine on taste Will you have Taste - impaired with Hydroxychloroquine., Question about RA and taste and smell issues." Rheumatoid. What are the side affects of hydroxychloroquinePlaquenil testing protocol One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The Risk of Retinal Toxicity with Plaquenil. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Raven and yally, thank you for the ideas, I think I will try taking the whole dose at bedtime as one of my favorite side effects of plaquenil is that it has cured my RA induced insomnia. If that doesn't work I will talk to my doctor about the lower dose-hopefully I can put that off until I am off the prednisone and not having flares. Presse Med. 1996 Feb 10;255213. Changes in taste and smell caused by hydroxychloroquine. Article in French Weber JC, Alt M, Blaison G, Welsch M, Martin T, Pasquali JL. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.