Chloroquine in treatment of hypercalcemia

Discussion in 'Canadian Pharcharmy' started by 21008, 16-Mar-2020.

  1. anton211 New Member

    Chloroquine in treatment of hypercalcemia


    For questions concerning RSS credit or the my CME system, please write to mycme [at] ccf [dot] org. Hypercalcemia is a condition in which you have too high a concentration of calcium in your blood.

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    Original Article from The New England Journal of Medicine — The Effects of Chloroquine on Serum 1,25-Dihydroxyvitamin D and Calcium Metabolism in Sarcoidosis. in the treatment of. In addition, reducing calcium intake to under 400 mg/day, reducing oxalate intake, and avoiding sun exposure are also recommended in treatment of hypercalcemia in granulomatous disease. Chloroquine is one alternative therapy that may also be considered. Although the mechanism in unclear, it is shown to impair granuloma formation. Despite the multitude of agents used at one time or another in its treatment 1 none have been practical, and only the adrenal cortical steroids and ACTH have been found to be effective. It is generally accepted that these 2 agents should be reserved for the rare seriously ill patient 1-6.

    It’s also important in blood clotting and bone health. Hypercalcemia makes it hard for the body to carry out its normal functions. Calcium is essential for the normal function of organs, cells, muscles, and nerves.

    Chloroquine in treatment of hypercalcemia

    Hydroxychloroquine - Wikipedia, Hypercalcemia, Anemia, and Acute Kidney Injury A Rare.

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  3. Hydroxychloroquine and chloroquine These oral antimalarial drugs have been used to treat sarcoidosis of the skin, lungs, and nervous system. They are used to treat the hypercalcemia seen with sarcoidosis. Patients on these drugs need occasional monitoring of their eyes by an ophthalmologist.

    • Sarcoidosis Treatment - Cleveland Clinic.
    • Chloroquine in the Treatment of Infectious Mononucleosis..
    • Chloroquine Side Effects Common, Severe, Long Term -.

    The treatment used depends on the cause and extent of hypercalcemia. Light hypercalcemia - treatment plasma calcium level less than 11.5 mg / dL less than 2.88 mmol / L, in which symptoms are minor, is determined after diagnosis. Correction of the original cause is performed. Arthritis, juvenile treatment 1 —Hydroxychloroquine is used in the treatment of juvenile arthritis {24}. Hypercalcemia, sarcoid-associated treatment 1 —Hydroxychloroquine is used to reduce urinary calcium excretion and the levels of 1,25-dihydroxyvitamin D in the serum of sarcoid patients who are unable to take corticosteroids {62}. Some patients are also treated with medications that decrease bone reabsorption, corticosteroids and chloroquine. Bisphosphonates are a group of drugs that are considered drugs of choice for cancer associated hypercalcemia and include pamidronate, ibandronate, etidronate, alendronate and risedronate.

     
  4. kent.avr Guest

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Hydroxychloroquine - Wikipedia Hydroxychloroquine Plaquenil Toxicity and Recommendations. The risk of toxic retinopathy in patients on long-term.
     
  5. Petrik New Member

    Retinal complications from HCQ are actually rare (at proper dosage) and, with good screening, the risk for visual loss is very low. Diagnosis and Management of Rheumatoid Arthritis. Taking Plaquenil for Rheumatoid Arthritis American College of Rheumatology Patient History Form
     
  6. Vavilon Moderator

    Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.

    How to Succeed in Plaquenil Screenings
     
  7. Reaver User

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Do not use Plaquenil without telling your doctor if you are breast-feeding. Our blog on Lupus and Pregnancy has much more valuable information on this topic. Back to top. We hope that this blog has been helpful in answering some of your questions about Plaquenil and other antimalarial drugs used to treat lupus.

    Hydroxychloroquine - I believe this drug causes false.