One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine use during pregnancy Plaquenil lupus pregnancy How much does plaquenil cost blue cross blue shield Newer guidelines state that daily dose 5mg/kg of real weight/day can lead to toxicity. Retinal toxicity is irreversible and can progress after cessation of hydroxychloroquine, thus early screening is important to limit potential vision loss. Baseline screening and annual screening after five years is recommended. The latest screening guidelines were published in 2016 by the American Academy of Ophthalmology Table 1. The most important risk factors are dosage and duration of use. Dosage greater than 5.0mg/kg over five years dramatically increases the risk of retinal toxicity, and high doses can be exceedingly dangerous. Plaquenil. The new guidelines- 2011 American Academy of Ophthalmology Offer new dosing and screening protocols How often for objective test screening? Baseline 5 years* Yearly after 5 years of initiating therapy *May consider screening sooner than 5 years if risk factors are present 2016. Who to screen for toxicity? High Risk It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil screening guidelines aao My Take on New Ocular Screening Guidelines for Plaquenil., How to Succeed in Plaquenil Screenings Can i take tylenol with hydroxychloroquinePlaquenil heart rateWhat is the filler in hydroxychloroquineChloroquine and g6pdAralene In 2011, the AAO published updated ocular examination guidelines for screening patients on Plaquenil therapy. 4 Recommended testing includes a comprehensive eye exam with an assessment of posterior segment via dilated funduscopy. Is Damage Still Occurring? - Review of Optometry. PowerPoint. Update on Plaquenil Testing. Update on Screening Recommendations for Hydroxychloroquine.. Mar 01, 2011 The revised screening guidelines recently released by the AAO are a bit more rigorous than those previously advocated, as they call for the use of newer, potentially more sensitive imaging modalities. By following these guidelines, and by maintaining a high index of suspicion, most cases of severe toxicity may be prevented. Aug 30, 2011 Newer guidelines state that daily dose 5mg/kg of real weight/day can lead to toxicity. Retinal toxicity is irreversible and can progress after cessation of hydroxychloroquine, thus early screening is important to limit potential vision loss. Baseline screening and annual screening after five years is recommended. AAO Screening Guidelines for Plaquenil. by S P. Check out my recent review/summary of the American Academy of Ophthalmology’s statement on the Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision from the Ophthalmology Journal 2016;186-1394.