These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Deubiquitinating enzyme chloroquine Plaquenil eye exam guidelines Hydroxychloroquine for sjogren's syndrome Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil immediate side effects Plaquenil Uses, Dosage & Side Effects -, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil and osteoarthritis Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil Side Effects - GoodRx. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. Sep 13, 2019 Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. seek immediate medical attention.