Hydroxychloroquine and nerve damage

Discussion in 'Canadian Drug' started by semenov, 28-Feb-2020.

  1. mitsno XenForo Moderator

    Hydroxychloroquine and nerve damage


    Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology.

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    It’s used in people with Sjogren’s syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. A rare complication of the commonly used rheumatoid arthritis drug hydroxychloroquine Plaquenil is injury to the retina the light-sensing portion of the back of the eye. The earliest sign of retinal changes from hydroxychloroquine is a decreased ability to distinguish between red and green colors.

    While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula.

    Hydroxychloroquine and nerve damage

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria

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  7. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

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    Ophthalmological ReactionsCardiomyopathy and Qt ProlongationHaematological ReactionsNeurological and Neuromuscular Reactions Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Hydroxychloroquine for more than five years and/or in high doses are at increased risk of damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Overall, around seven patients out of every 100

     
  8. kds452 XenForo Moderator

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  9. Inferion User

    Hydroxychloroquine overcomes tamoxifen resistance in breast. In MCF7-RR cells, which are resistant to tamoxifen, the combination of hydroxychloroquine and tamoxifen significantly reduced tumor size, but neither hydroxychloroquine nor tamoxifen alone significantly reduced tumor size.

    Hydroxychloroquine Indications, Side Effects, Warnings.