Tamoxifen lung cancer

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    Tamoxifen lung cancer


    : Tamoxifen is an antiestrogen with proven efficacy and low toxicity in the treatment of breast cancer. However, tamoxifen has been shown to exert a number of nonhor-monalas well as hormonal effects. One nonhormonal effect of tamoxifen is the induction of transforming growth factor-β (TGF-β) secretion. TGF-β has been implicated in the pathogenesis of radiation-induced fibrosis. : Data from 196 women were included in the analysis. Eighty-four women were postmeno-pausal patients who participated in a randomized trial testing tamoxifen as an adjuvant to postmastectomy radiotherapy. The radiotherapy technique employed an 8-MV photon field covering the axillary and the infraclavicular and supraclavicular regions of the affected side of the chest; the chest wall was treated with an abutted electron field. Hi everyone, This is my first post on this group, although I've been reading the posts for awhile. My 79-year-old mother was diagnosed with stage IV, non-small cell lung cancer in Feb 2011. She's being treated at UT Southwestern in Dallas, TX. she was started on Alimta, which stabilized her cancer for awhile. After a two-month holiday from the chemo, her doc has started her on Tarceva. Her doc doesn't think it's out of the realm of possibilities that my mom's cancer was caused by taking HRT for 17 years. Ever since I read the study about Tamoxifen and estrogen-driven lung cancer, I have been bugging my mom's doc about putting her on it. She won't do it, however, since the FDA has not approved Tamox for lung cancer. Has anyone's oncologist prescribed Tamoxifen for lung cancer?

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    Tamoxifen is the oldest of the hormonal therapies, drugs that block the. Tamoxifen won't work on hormone-receptor-negative breast cancer. Ever since I read the study about Tamoxifen and estrogen-driven lung cancer, I have been bugging my mom's doc about putting her on it. Efficacy of tamoxifen in combination with docetaxel in patients with advanced non-small-cell lung cancer pretreated with platinum-based chemotherapy.

    Previous studies have shown that women undergoing hormone replacement therapy to boost oestrogen during menopause showed an increased risk of dying from lung cancer. Based on the hypothesis that blocking oestrogen might also cut lung cancer death risk, researchers examined data from 6,655 women diagnosed with breast cancer between 19 in Switzerland's Geneva Cancer Registry. Close to half of those women, 3,066 (46%) were given anti-oestrogen drugs. The registry The registry's Elisabetta Rapiti, lead author of the study in Cancer, followed all those subjects until December 2007 and looked at how many developed lung cancer and how many died from lung cancer. Rapiti found that among those taking anti-oestrogen drugs, there were 87% fewer deaths from lung cancer when compared to the general population. When she looked simply at how many women in the study were diagnosed with lung cancer, she found no significant difference between those taking anti-oestrogen therapy and those who were not. "Our results support the hypothesis that there is a hormonal influence on lung cancer which has been suggested by findings such as the presence of oestrogen and progesterone receptors in a substantial proportion of lung cancers," said Rapiti. Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer). Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. Tamoxifen may also be used for purposes not listed in this medication guide. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin). Before using this medicine, tell your doctor if you have liver disease, high triglycerides (a type of fat in the blood), a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment.

    Tamoxifen lung cancer

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  6. Reviewed by Laura J. Martin, MD. Jan. 24, 2011 -- Tamoxifen, the medication long used to prevent the growth of breast cancer tumors, also appears to reduce the

    • Tamoxifen May Cut Lung Cancer Deaths -.
    • Efficacy of tamoxifen in combination with docetaxel in patients with..
    • Tamoxifen Citrate - National Cancer Institute.

    Brand tamoxifen and lung cancer symptoms online india. Oncology journals worldwide as painkillers can grow in the uk that is essential for breast cancer. Background Mounting evidence indicates that women have a different susceptibility to lung cancer than men. In particular, female. Tamoxifen and lung cancer - Forget about inconvenient health issues with remedies presented online effective brand medications, food supplements, vitamins.

     
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