Sertraline vs venlafaxine

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    Sertraline vs venlafaxine


    The use of antidepressants in adults with depression or generalised anxiety disorder (GAD) has been addressed by the NICE guidelines on depression in adults (which is being updated; publication expected May 2017), depression in adults with a chronic physical health problem and GAD and panic disorder in adults. The NICE guideline on common mental health disorders brings these recommendations together and can be used to help clinicians, commissioners and managers develop effective local care pathways for such people. See the NICE Clinical Knowledge Summaries on depression and GAD for general overviews of these conditions. The NICE pathways on depression and GAD bring together all related NICE guidance and associated products on antidepressants in a set of interactive topic‑based diagrams. See also specific NICE guidelines on antenatal and postnatal mental health, depression in children and young people (recommendations on psychological therapies and antidepressants were updated in March 2015) and social anxiety disorder. The NICE quality standards on depression in adults, depression in children and young people, and anxiety disorders describe concise sets of prioritised statements designed to drive measurable quality improvements within these areas. NICE advocates a stepwise approach to managing common mental health disorders. uses cookies to improve performance by remembering your session ID when you navigate from page to page. Please set your browser to accept cookies to continue. This cookie stores just a session ID; no other information is captured. Accepting the NEJM cookie is necessary to use the website.

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    J Clin Psychiatry. 2005 Oct;66101312-20. Randomized trial of sertraline versus venlafaxine XR in major depression efficacy and discontinuation symptoms. Sertraline-venlafaxine. From Psychiatrynet. Before day 1 gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is 50 mg/day. Sertraline is an antidepressant in the SSRI class. It's used for depression, anxiety, panic disorder, OCD, and a number of other conditions.

    Despite the well-known efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) in the treatment of major depressive disorder, there is a lack of indications for each drug in different groups of patients. The aim of this study is to investigate the possible role of clinical sociodemographic factors as moderators of clinical response to venlafaxine (SNRI) and sertraline (SSRI). Research was performed on Medline and EMBASE for randomized control trials in English focused on sertraline and venlafaxine in the treatment of major depressive disorder and 59 studies were included. Clinical efficacy of each treatment was assessed on the basis of Hamilton Depressive Rating Scale and Montgomery–Asberg Depression Rating Scale. A metaregression analysis was performed to evaluate the role of clinical and sociodemographic factors as moderators of outcome, calculating the effect of each variable with the random-effects method. Gender, ethnicity and duration of depressive episode could have a role in prediction of clinical response to both antidepressants. Venlafaxine seems to have better effects in females and in Caucasian patients. Adverse events over 6–12 week trial durations tend to be mild and comparable to those observed in trials of middle aged depressed people. Notably, only one trial has attempted to assess long term efficacy or prophylaxis compared to placebo. In contrast, this trial was conducted in a very old, medically frail population, with significant depressive symptoms but heterogeneous diagnoses. Nearly half were cognitively impaired, some to a moderate degree. This is the milieu in which the Penn group’s trial needs to be assessed. As the authors acknowledge, the trial lacks a placebo group that would have established “assay sensitivity” or external validity. In the absence of evidence that either sertraline or venlafaxine is more effective than placebo in this medically frail population, the trial can provide evidence only for relative overall effectiveness of sertraline compared with venlafaxine.

    Sertraline vs venlafaxine

    Venlafaxine vs sertralinezoloft - Patient, Sertraline-venlafaxine - Psychiatrynet

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  4. Q What are the relative benefits and risks of sertraline and venlafaxine in depressed. In the absence of evidence that either sertraline or venlafaxine is more.

    • Venlafaxine offers no benefit over sertraline and is less well tolerated..
    • Sertraline - The Drug Classroom.
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    Feb 11, 2009. Mirtazapine, escitalopram, venlafaxine, and sertraline were among the. There are plenty of trials comparing fluoxetine vs. venlafaxine, but. Zoloft sertraline and Effexor venlafaxine are antidepressants used to treat depression. Sertraline Versus Venlafaxine XR in Major Depression. J Clin Psychiatry, October 2005. 1313 he comparative efficacy of selective serotonin reup-.

     
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