Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Hydroxychloroquine inr Tamoxifen and hydroxychloroquine Plaquenil for babesia Basic description of chloroquine Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Plaquenil has long been associated with retinal toxicity which can lead to vision loss. In particular it affects the macular region of the retina which is responsible for central vision. Very early on toxicity is usually asymptomatic detected only by a spectral domain optical coherence tomographer and a macular visual field test. Visual field defect is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Methotrexate, and have Osteoporosis. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil visual field Humphrey visual field findings in hydroxychloroquine toxicity, Plaquenil Examination - McKinney Eye Works Does hydroxychloroquine cause demyleination Plaquenil Hydroxychloroquine may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. In patients of Asian descent, it is recommended that visual field testing be performed in the central 24 degrees instead of the central 10 degrees. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Will you have Visual field defect with Plaquenil - eHealthMe. Plaquenil Side Effects on Your Eyes and Vision. Every facet of Customer Care at ZEISS is designed to protect your investment in your equipment. Whether it is a high-end surgical microscope, an ophthalmic laser, diagnostic equipment, or radiotherapy system, we provide timely, responsive services through a national network of highly skilled technicians. A 45-year-old black female presented with no ocular or visual complaints. Her ocular history was unremarkable. However, her medical history was significant for a recent diagnosis of lupus. Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil hydroxychloroquine, Sanofi-Aventis therapy. I was told from the start by my rheumatologist I would have to have eye exams including visual field exams every six months due to the plaquenil therapy. My first two exams did include these tests. But my next six month appointment is coming up, and they told me I didn't need the visual field test this time so the appointment would be shorter.