Additionally, another exception occurred while executing the custom error page for the first exception. To investigate the application of ultra-widefield fundus autofluorescence (UWF-FAF) imaging in evaluating hydroxychloroquine (HCQ) retinopathy and to report peripheral autofluorescence findings in Asian patients with this condition. Patient population: 58 eyes of 29 patients with HCQ retinopathy. Return of chloroquine antimalarial efficacy in malawi Plaquenil pap frequency How safe is plaquenil Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Although multifocal electroretinogram mfERG and fundus autofluorescence FAF are not currently primary tests used in the evaluation of Plaquenil retinal toxicity, they may be beneficial when the diagnosis or findings are enigmatic or an adjunct test is warranted. Fundus autofluorescence patterns in various stages of hydroxychloroquine retinopathy. Classic bull’s-eye maculopathy appearance A. As the RPE atrophies, the FAF intensity in the pericentral macula changes to a mottled, or speckled appearance B, and eventually coalesces into dark areas of absence of FAF signal once the cells have died C. The sensitivities of detecting retinopathy using the 2 modalities were compared. Observation procedures: UWF-FAF imaging was performed, and the images were compared to conventional FAF images obtained using a confocal digital ophthalmoscope. Plaquenil maculopathy fundus autofluorescence Clinical applications of fundus autofluorescence in retinal., How to Succeed in Plaquenil Screenings Chloroquine resistant malaria Plaquenil Maculopathy. Download 1.8 mb. Fundus camera Heidelberg Spectralis. Autofluorescence photograph of plaquenil toxicity. Related files. Plaquenil Maculopathy - Retina Image Bank. Multimodal Imaging in Plaquenil Toxicity. Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Plaquenil-induced toxic maculopathy was first described in 1967. Because the retinal damage from plaquenil is usually irreversible if present for a more prolonged period of time, it is important to detect the disease in its early stages. Fundus autofluorescence; Multifocal electroretinograms mf ERG. Early detection of any maculopathy is critical to prevent central visual loss. The Retina Group of New York provides all of these testing modalities and is the only center on Long Island with mf ERG. Treatment. The treatment for early toxicity usually requires stopping Plaquenil. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to.