Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Chloroquine diphosphate salt Hydroxychloroquine-induced pigmentation I was diagnosed with Discoid lupus in 2009 and I began using Plaquenil once I stopped breastfeeding. Initially, the only difference I noticed was my hair stopped falling out. After taking Plaquenil for a less than a year my face and neck started turning black. My dermatologist is convinced that Plaquenil is the culprit and just recently. Lupus Treatment. Lupus Medications and Treatment Options;. Anti-malarials are particularly useful in treating discoid lupus, subacute cutaneous lupus, and mouth sores associated with lupus; they are also effective in treating rheumatoid arthritis and Sjogren’s syndrome. All information contained within the Johns Hopkins Lupus Center. Despite adequately documented evidence of the effectiveness of the antimalarials quinacrine and chloroquine in the treatment of discoid lupus erythematosus, * a significant number of patients receiving these drugs derive little or no benefit from them, either because of side-effects of sufficient severity to compel discontinuance of medication, or simply because of lack of therapeutic effect. This medicine is not effective against all strains of malaria. Malaria is common in areas such as Africa, South America, and Southern Asia. Discoid lupus treatment plaquenil Cutaneous Lupus Erythematosus Diagnosis and treatment, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Plaquenil ankylosing spondylitisPlaquenil and foot pain Some studies have shown both topical tacrolimus and pimecrolimus to be effective alternatives in the treatment of cutaneous lupus erythematosus CLE, including DLE lesions. Sugano M, Shintani Y, Kobayashi K, et al. Successful treatment with topical tacrolimus in four cases of discoid lupus erythematosus. Discoid lupus erythematosus - Treatment algorithm BMJ Best Practice. Plaquenil in the Treatment of Discoid Lupus Erythematosus A.. Discoid lupus erythematosus DermNet NZ. Nov 25, 2019 Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Alternative therapies, anecdotal reports, and small, open-label trials as reported by. Background. Discoid lupus erythematosus DLE is a form of skin inflammation which occurs particularly on sun-exposed skin and can cause forms of cutaneous lupus erythematosus are most common in women of childbearing age, which is important because some treatments, including thalidomide and acitretin, can cause birth defects, and hydroxychloroquine may cause damage to the eye or ear.